Molecular Systems Engineering of Algae – The Construction of Molecular Factories Based on a Phototroph Platform
The main goal of this project is to engineer the cell surface of algae, to generate new phenotypes and to construct molecular factories based on a phototrophic platform.
Algae offer unique opportunities as programmable (by light) CO2-fixing organisms that can be grown for example, on brackish or waste water with concomitant CO2 fixation from fossil fuel power plants and the ability to produce biofuels or value added chemicals.
The question raised by this project is if this potential can be leveraged by Molecular Systems Engineering to increase the efficiency, sustainability and productivity of the phototrophic organisms. Ultimately, the goal is to construct molecular factories based on a phototroph platform.
C. E. Housecroft, C. G. Palivan, K. Gademann, W. Meier, M. Calame, V. Mikhalevich, X. Zhang, E. Piel, M. Szponarski, A. Wiesler, A. Lanzilotto, E. C. Constable, A. Fanget, R. Stoop “‘Active surfaces’ as Possible Functional Systems in Detection and Chemical (Bio) Reactivity“ Chimia 6, 402 (2016). [Link]
Read more about the Gademann-Group here.
The phototroph-based platform will be developed in collaboration with and used by projects lead by Daniel Müller, Wolfgang Meier, Sven Panke, Michel Calame, Thomas R. Ward, Martin Fussenegger, Dimitrios Fotiadis, Roderick Lim, Stefan Matile, Marcel Mayor, Francesco Stellacci, and Catherine Housecroft.